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Antibiotics: Challenges, Mechanisms, Opportunities


Huge Savings Item! Free Shipping Included! Save 18% on the Antibiotics: Challenges, Mechanisms, Opportunities by Timothy Wencewicz Christopher Walsh at Diseasome. Hurry! Limited time offer. Offer valid only while supplies last. A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges,


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A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance

Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets.

This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics.

Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions:

  • What are antibiotics?
  • Where do antibiotics come from?
  • How do antibiotics work?
  • Why do antibiotics stop working?
  • How should our limited inventory of effective antibiotics be addressed?

Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.

Additional Information

Manufacturer:Amer Society for Microbiology
Brand:Timothy Wencewicz Christopher Walsh
Publisher:Amer Society for Microbiology
Studio:Amer Society for Microbiology
EAN:9781555819309
Item Weight:0 pounds
Item Size:1 x 10 x 10 inches
Package Weight:2.2 pounds
Package Size:7 x 1 x 1 inches

Antibiotics: Challenges, Mechanisms, Opportunities by Timothy Wencewicz Christopher Walsh

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Antibiotics: Challenges, Mechanisms, Opportunities

Brand: Timothy Wencewicz Christopher Walsh
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